抗酒石酸酸性磷酸酶(TRAP,tartrate-resistant acid phosphatase)为破骨细胞的标志酶,特异地分布于破骨细胞中,为破骨细胞所特有。通常作为鉴别破骨细胞的重要标志物,使破骨细胞呈红色。Kamiya艾美捷抗酒石酸酸性磷酸酶TRAP染色试剂盒,经众多Nature文章使用认证!
Kamiya艾美捷抗酒石酸酸性磷酸酶TRAP染色试剂盒应用:
① 破骨细胞TRAP染色
② 破骨细胞培养上清液中TRAP活性的测定
Kamiya艾美捷抗酒石酸酸性磷酸酶TRAP染色试剂盒Nature文章结果鉴赏:
①【Nature Medicine, IF=87.2】
TRAP stain: TRAP染色 (osteoclasts (o/c))
图1
② 【Nature Biomedical Engineering, IF=29.2】A multi-organ chip with matured tissue niches linked by vascular flow
TRAP Activity: TRAP活性
图2
更多发表文章:
Kim, Jinkoo, et al. "Erythropoietin mediated bone formation is regulated by mTOR signaling."Journal of cellular biochemistry113.(2012): 220-228.
Lee, Yu-Chen, et al. "Src family kinase/abl inhibitor dasatinib suppresses proliferation and enhances differentiation of osteoblasts."Oncogene 29.22 (2010): 3196-3207.
Lu, Yi et al. "Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone". Clinical & experimental metastasis vol.26,2 (2009): 161-9. doi:10.1007/s10585-008-9226-7