目录

1.患者基本信息

2.生物标记物量化值

3.认知评估

4.解剖结构量化值

5.Other

6.上述各信息的bl值

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1.患者基本信息

RID (Participant roster ID) ex. 2、PTID (Original study protocol) ex. 011_S_0002、VISCODE (Visit code) ex. bl、SITE ex. 11、COLPROT (Study protocol of data collection) ex. ADNI1、ORIGPROT (Original study protocol) ex. ADNI1、EXAMDATE (Date) ex. 9/8/2005、DX (Diagnosis) ex. CN

AGE 54.4-91.4、PTGENDER (Sex) Female \ male、PTEDUCAT (Education) 4-20、PTETHCAT (Ethnicity) 、PTRACCAT (Race)、PTMARRY (Marital)

2.生物标记物量化值

ABETA (CSF ABETA)、 APOE4 (0, 1, 2)、FDG (Average FDG-PET of angular, temporal, and posterior cingulate)、PIB (Average PIB SUVR of frontal cortex, anterior cingulate, precuneus cortex, and parietal cortex)、 AV45 (Reference region - florbetapir mean of whole cerebellum. Regions defined by Freesurfer; see Jagust lab PDF on LONI for details)、TAU (CSF TAU)、PTAU (CSF PTAU)

3.认知评估

CDRSB (Clinical dementia rating sum of boxes)、MMSE (Mini-mental state evaluation)、FAQ (Functional Activities Questionnaire)、MOCA (Montreal cognitive assessment)、LDELTOTAL (Logical Memory - Delayed Recall)、DIGITSCOR (Digit Symbol Substitution)

ADAS11、ADAS13、ADASQ4 (ADAS Delayed Word Recall)

mPACCdigit (ADNI modified Preclinical Alzheimer's Cognitive Composite (PACC) with Digit Symbol Substitution)、mPACCtrailsB (ADNI modified Preclinical Alzheimer's Cognitive Composite (PACC) with Trails B)、TRABSCOR (Trails B)

RAVLT (forgetting)、RAVLT_immediate (sum of 5 trials)、RAVLT_learning (RAVLT Learning (trial 5 - trial 1))、RAVLT_forgetting (RAVLT Forgetting (trial 5 - delayed))、RAVLT_perc_forgetting (RAVLT Percent Forgetting)

EcogPtMem、EcogPtLang、EcogPtVisspat、EcogPtPlan、EcogPtOrgan、EcogPtDivatt、EcogPtTotal、EcogSPMem、EcogSPLang、EcogSPVisspat、EcogSPPlan、EcogSPOrgan、EcogSPDivatt、EcogSPTotal

4.解剖结构量化值

IMAGEUID、Ventricles 心室、Hippocampus 海马体、WholeBrain 、Entorhinal 嗅内区、 Fusiform 梭状回、 MidTemp 颞中回 、 ICV → 可以和 PET数据的定量数据 一起分析，对结构向数据和功能向数据的结合使用可以有效降低自然衰老带来的个体间差异

5.Other

FSVERSION (FreeSurfer Software Version)、FLDSTRENG (MRI Field Strength)、Month (Months since baseline)、M (Months since baseline)

6.上述各信息的bl值